• Sign In
  • |
  • Register
About the role
The University of Leicester is committed to international excellence, world-changing research and high quality, inspirational teaching. Recently, the MRC in partnership with the Universities of Leicester, Warwick, Nottingham and Birmingham has invested into a state-of-the-art CryoEM facility at the Leicester Institute for Structural and Chemical Biology (LISCB), one of four new, flagship Research Institutes of the University of Leicester.
 
LISCB comprises over 20 research groups drawn from several departments, including the Department of Molecular and Cell Biology, and brings together internationally renowned research using structural biology, chemical biology and single molecule methods to investigate major challenges in fundamental biological processes into a single world-leading unit.

We are looking to recruit an experienced postdoctoral researcher to the group of Prof Daniel Panne to join a programme of research to investigate higher–order signaling complexes that are important in inflammatory/cancer signaling, innate immunity and gene/chromatin regulation.

For examples of recently published work please see e.g. DOI 10.1016/j.celrep.2013.01.034, DOI 10.1038/nsmb.2642, DOI 10.15252/embj.201694105 and DOI 10.1016/j.celrep.2016.01.078. Other work, describing insights into chromatin modification and links to metabolism as well as the chromatin assembly machinery has been published recently 10.1038/nchembio.2217 and 10.7554/eLife.23474. Additional recent work concerns structural biology of signaling complexes in the innate immune system 10.1073/pnas.1718426115.

The research will involve expressing and purifying proteins from recombinant sources, gaining structural insights using electron microscopy and X-ray crystallography and using a wide range of biochemical and biophysical techniques to explore their function.

You will develop your own original research projects, in line with the aims of the research programme and assist other members of the team. You will write up your research findings for dissemination amongst the research team and the broader international community and make presentations at scientific meetings in the UK and overseas.

About you

The successful applicant should hold a PhD, have a strong background in biochemical or structural analysis of proteins and be able to take a role in experimental design and shaping the direction of the research programme.

Additional information
In return for your hard work, we offer a working environment that is committed to inclusivity, through promoting equality and valuing diversity. We offer a competitive salary package with excellent pension scheme, a generous annual leave allowance and an online portal that offers a range of lifestyle benefits and discounts. Located close to Leicester city centre, our award winning campus benefits from a wide range of cafes, a fully equipped sports centre and nursery facilities. Further information regarding our extensive range of staff benefits is available here.

Informal enquiries are welcome and should be made to Professor Daniel Panne on tel: +44 (0)116 229 7408 or email:  daniel.panne@le.ac.uk